ncRNA name | hsa-let-7c |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | human RB cell lines Y79 and SNUOT-Rb1 |
Methods | microarray |
Expression pattern | up-regulated |
Functional description | 22 miRNAs were upregulated in SNUOT-Rb1 cells than Y79 cells. More than half of top 10 mRNA targets of hsa-miR-10b, hsa-miR-29a, hsa-miR-29b, hsa-miR-29c, and hsa-let-7c in SNUOT-Rb1 cells were related with biological processes, which could affect the growth patterns of cells: cell adhesion, cell cycle, cell death, and cell division. |
PubMed ID | 21941147 |
Year | 2011 |
Title | Differential profiles of microRNAs in retinoblastoma cell lines of different proliferation and adherence patterns. |
Drug-related ncRNA | NO |
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